Houlton got things started with a 56-48 win over Bangor, then followed with a 62-42 win over Camden Hills. Houlton next beat Lawrence, 47-34 to advance to the championship of the South bracket.
In the regional title, the Shires again faced Lawrence, this time beating them 36-22.
In the championship game, Houlton rallied to beat Hampden Academy 62-60 in a thrilling game.
“All of the seven girls played extremely well as a team and the five games they played were all against class A or AA competition,” said coach Rob Moran.
Team members are, front row from left, Kristen Brewer, Jamie Brown, Rylee Warman and Emma Peterson; and back, Assistant Coach Katie Condon, Kolleen Bouchard, Aspen Flewelling, Kristen Graham, Coach Moran and Assistant Coach Kyle Bouchard.